MILK SA: R & D STATUS QUO AND OUTLOOK FOR THE STATUTORY LEVY CYCLE OF 2018 TO 2021.

  1. POINT OF DEPARTURE:

     

    1. Statutory resolution: “To give effect to the purpose of designated levies to R & D as per Regulation R57 of 30 January 2009, which states: “Research and development are required to promote not only the viability of the dairy industry but also to promote the achievement of the other objectives of the Act as set out in section 2 (2) of the Act: Research is fragmented and action is required to ensure coordination and that research and development are functional in respect of the strategic direction of the industry, namely broadening of the market for milk and other dairy products, improvement of the international competitiveness of the South African industry, and empowerment of previously disadvantaged individuals. Furthermore, action is required to promote the practical application of local and international research and development in South Africa”.

    2. Principle: R & D to achieve these goals must address demonstrable problems, risk or need which impact on profitability, sustainability and continuous improvement of the dairy industry, as well as broadening the market for dairy products. Therefore the R & D must be solution focussed. However, before any research will be sanctioned, an investigation should be commissioned to ascertain whether appropriate managerial measures leading on to the research question are or have been implemented. Furthermore, a thorough literature study and supporting information should prove that the knowledge is not adequate to provide effective extension and/or training of the intended recipients.

       

  2. STRUCTURE TO CO-ORDINATE AND MANAGE R & D:

    The structure shown in Annexure 1 replaced the structure until 2016 and is expected to be functional during the period until 2021. Explanations are in the footnotes.

     

    The Dairy R & D Committee via the Management Committee is advised by members of the Dairy Research Forum and other expertise. The MPO and SAMPRO through their structures feed in demonstrable problems/needs to the Management Committee, which screens the proposals with regard to relevance and priority. Those proposals meeting the criteria are presented to the Dairy R & D Committee for further evaluation and allocation to suitable expertise and capacities to be developed into R & D protocols where appropriate. The Dairy R & D Committee finally proposes funding to the Milk SA Board.

     

                  Through networking and official agreements where applicable, but without being

                  descriptive, it is endeavoured to align the R & D agendas of research capacities in

                  the provinces, the ARC, SA Studbook, tertiary institutions etc, to the national goals

                  and objectives of the industry. In terms of funding, the networks allow access to

                  government funds, in addition to strengthening the possibility of obtaining access

                  to dedicated funding sources as made available by DAFF, DTI, DST and other

                  institutions. This may contribute significantly towards supplementing a limited

                  levy allocation to R & D, thereby supporting a sustainable R & D programme.  The

                  network requires continuous strengthening towards 2021 to ensure effective service

                  to the dairy industry.

     

  3. R & D FIELDS IDENTIFIED AND STRUCTURAL ARRANGEMENTS:

    The fields identified are:

  • Animal health, bio-security and welfare

  • Dairy products and nutraceuticals

  • Feed sources and animal nutrition

  • Food safety and quality

  • Genetics, physiology and reproduction

  • Markets and techno-economics

  • The environment.

     

  1. BUDGET ANTICIPATED FOR PERIOD 2018 to 2021:

    Not attached to this copy because of confidentiality reasons.

  2. CURRENT PROJECTS:

    1. R & D Field: Animal health, bio-security and welfare:

      1. Mastitis

        1. Project by UP (Onderstepoort), started in 2016 and is envisaged to be completed in 2019.

          Project title: Resistance to available antibiotics in lactating cows with mastitis.

          Project leader: Dr Martin van der Leek.

          Objectives in brief: Characterization and prevalence of mastitis-causing organisms, testing in vitro sensitivity of the organisms to antibiotics on the market, observing mastitis management programmes on farms and investigating sources of environmental and milking parlour contamination.

           

        2. Project by UKZN (Plant Pathology), started in 2015 and is envisaged to be completed in 2019.

          Project title: Investigating alternative methods such as bacteriophages and bacteriocins to control mastitis organisms.

          Project leader: Prof Mike Laing [plus post-doc Dr Iona Basdew].                                                                        Objectives in brief: Classify and determine efficacy of bacteriophages against Staphylococcus aureus where after other prominent mastitis-causing pathogens will follow; isolate bacteriocins from Staphylococcal and Streptococcal strains; do in vitro screening and efficacy tests; test promising isolates in vivo; develop commercial products.

          Comments: Promising bacteriophage isolates were identified in a PhD study (Iona Basdew) in 2013. Other isolates with or without bacteriocins are investigated to develop a mix to facilitate non-adaptation by mastitis pathogens. The mix is envisaged to lead to a commercial product.

           

      2. Fasciolosis (liver fluke):

        1. Project by UP (Onderstepoort), started in 2015 and is envisaged to be completed in 2019.

                 Project title: Fasciola hepatica: Impact on dairy production and

                 sustainable management on selected farms in South Africa.

                 Project leader: Dr Jan van Wyk.

                 Objectives in brief: Investigation of prevalence, seasonal trends,

                 mode of transmission of the parasite, management programmes

                 followed by farmers and anthelminthic efficacy for treatment. Some

                 emphasis is put on the control and management of the intermediate

                 snail host which is perceived to be the preferred way of controlling

                 Fasciolosis.     

           

        2. Project by UKZN (Plant Pathology), started in 2016 and is envisaged to be completed in 2020.

                                       Project title: Integrated control of liver flukes of cattle using

                                       botanical extracts and bio-control agents.

                                       Project leader: Prof Mark Laing [plus post-doc Dr Mawahib Ahmed]                                                                           

                                       Objectives in brief: Chemical extracts from plants with known

                                       medicinal characteristics in addition to potential bio-control agents

                                       such as fungi which attack the host snail are evaluated both in vitro

          sp;                          and in vivo.

                                      Comments: Chemical extracts used in the PhD study were effective in

                                      controlling sheep nematodes. Some are investigated to develop

                                      commercial products.

                                      

      3. Brucellosis:

        1. Project by the CSIR (Biosciences), started in 2016 and is envisaged to be completed in 2019.

          Project title: Point-of-care diagnostics for Bovine Brucellosis.

                                     Project leader: Dr Phiyani Lebea. 

                               Objectives: The point-of-care diagnostics for Bovine Brucellosis

                               propose establishment of a Brucella detection protocol that could be

                               designed for quick and initial verification on-farm. The main objective

                               is to develop two protocols, the first being a lateral flow (strip based)

                               immunoassay for detection of Brucellosis in milk samples and the

                               second being a workflow protocol for bulk milk testing.

                               Comments: The point-of-care identification of Brucella is based on a

                               device and lateral flow immuno-assay antigen-antibody methodology

                               and is tested in association with a dairy company in the Eastern Cape.

                                      

    2. R & D Field: Food safety and quality, plus Feed sources and animal nutrition:

      1. Milk flocculation:

        1. Project by UFS, started in 2016 and is envisaged to be completed in 2019. Project title: The significance of proteolytic psyghrotrophs as a cause of milk flocculation/protein instability                                                                       Project leader: Prof Celia Hugo, UFS.

          Objectives in brief: Psyghrotrophs are implicated for proteolysis since they can survive low temperatures in milk equipment; therefore the study to understand their possible relationship with milk flocculation.

          Comments: A rapid detection method for psyghrotrophs has been developed which should facilitate further study and may prove to become standard in processing plants.

           

        2. Project by UFS, started in 2016 and is envisaged to be completed in 2019.

          Project title: The impact of proteases and chemicals on milk flocculation Project leader: Dr Jacobus Myburgh, UFS.

          Objectives in brief: During heating for extended shelf life purposes enzymatic and other molecular changes can occur which may contribute to milk flocculation. These changes and relationships are studied.

          Comments: There is careful networking with Project 5.2.1.1 to distinguish proteolytic activity by psychrotrophs and enzymatic activity.

           

        3. Project by WCDA (Outeniqua), started in 2017 and is envisaged to be completed in 2019.                                                                                              Project title: The effect of anion/cation difference and potassium content of the diet on heat stability of milk.                                                                                                                   Project leader: Prof Robin Meeske, WCDA

          Objectives in brief: To vary the mineral, DCAD and other nutrients in cow diets to study possible reasons of milk flocculation on farm.

          Comments: Costs are covered by the WCDA budget, with the Milk SA R & D budget contributing only analytical costs.

           

    3. Genetics, Physiology and Reproduction:

      1. Genetic and performance monitoring programme:

        1. Analysis of automated systems:

                                      Project started in 2017 and is envisaged to be completed in 2019.

                                      Nature of project: Statistical trend monitoring of participating farmer

                                      results over time to establish progress of critical indicators.         

                                      Comments:  In the initial phase a Masters student (Anton Gresse) of

                                      UP evaluates appropriate methodology for evaluation together with

                                      a statistician and test the application with data of two farms. This

                                      may serve as a template for data of other farmers. This phase will be

                                      the initial investigation towards the programme envisaged in item

                                      6.1.1.

                                     

        2. Literature study on residual feed intake (RFI):

          Dr Carel Muller was contracted to do a literature study and make recommendations as to the applicability of what is envisaged in item 6.1.1.2.

          The study was completed in February 2017.

           

                        5.3.1.3. Genomic selection:

                                      Project started in 2017 and is envisaged to be completed in 2019.

                                      Nature of project: Reference populations are developed with

                                      genomic and phenotypic data which will form the basis to develop

                                      GEBV values for SA bulls.

                                      Comments: The project is funded by TIA and is conducted by the

                                      Livestock Genomics Consortium on behalf of the Dairy Industry, with

                                      managerial support from the MPO. As such, it is not a R & D project

                                     of Milk SA, but the outcomes are important within the context of the

                                     Genetic and Performance Programme. Several sub-projects with

                                     specific objectives are conducted.

                                      These are:

                                      DGP001: Makgahlela, M L. (ARC) - Genomic evaluation of dairy traits

                                      as a basis for accelerating food production in SA dairy cattle.

                                      DGP002: Makgahlela, M L. (ARC) - Determination of the genetic

                                      aspects of heifer and cow fertility in South African dairy cattle

                                      populations.

                                     DGP003: Joubert, R.C. (UP PhD study) - A genomic approach for an

                                     improved understanding of mastitis susceptibility in South African

                                     Holstein cattle.

                                     DGP004: Visser, C. (UP) - Genomic inbreeding estimation and

                                     effective population size of five SA dairy breeds.

                                     DGP005: Banga, C. (ARC) - Application of genomic technology for

                                     Accelerated genetic improvement of small holder and emerging dairy

                                     herds.

           

           

  3. PROJECTS APPROVED IN PRINCIPLE:

    6.1. Genetics, Physiology and Reproduction:

            6.1.1. Genetic and performance monitoring programme:            

                       Motivation: The Dairy Industry must support and encourage progress in

                       the SA Dairy Herd in terms of genetic progress, output, efficiency and

                       economic sustainability. The programme is to consider a genetic

                       improvement and performance programme with development and

                       ownership of an extensive database that include automated systems, in

                       addition to milk recording data and other appropriate methods (e.g. RFI

                       and genomics).

                 

                 6.1.1.2.  Selection based on residual feed intake (RFI):

                                Depending on recommendations from item 5.3.1.2 and feasibility the

                                Project will start in 2018 and is envisaged to be completed in 2021

                                Nature of project: Data acquisition, statistical analysis,

                                demonstrations and monitoring on station and farm.

                                Comments: A project leader will be identified to drive the project,

                                develop prediction equations and interact with participating farmers.

               6.2.  Food safety and quality:

                       6.2.1.   Preventing/removing biofilms and food-borne pathogens in milk lines:

                                    Motivation: Biofilm and spore-forming organisms are implied in

                                    unsatisfactory shelf life of long-life milk. Some of them may be food

                                    - borne pathogens and therefore a (bio-security) food safety risk (e.g.

                                    Listeria and E.coli). The biofilm organisms are also associated with

                                    mastitis-causing pathogens and, because of protease activity, probably

                                    also with the problem of milk flocculation. Biofilms are normally

                                    removed with sanitizers or steam sterilization, UV and hydrogen

                                    peroxide depending on position in the milk line, structure of equipment

                                    and practicality. Biofilm formation and spore-forming organisms are

                                    increasing which most probably indicates that cleansing and sanitizing

                                    are not done properly or less likely that current methods employed and

                                    sanitizers on the market are less effective. Therefore methodologies and

                                    management procedures for farmers and processors should be

                                    investigated and if necessary, new or other sanitizers and alternative

                                    methods should be considered. 

                    Comments: A literature review will be funded in 2018 to establish the

                     extent of the problem, develop hypotheses and submit protocols for

                     2018 and onwards. For the immediate future the possible linkage of

                     biofilms with milk flocculation is important, but this will be pursued only

                     if the statistical analysis of the database mentioned in item 7.4.1

                     provides evidence to that effect.

                    

  1. PROJECTS ANTICIPATED:

    1. Animal health, bio-security and welfare:

      1. Rapid disease detection:

        Motivation: The rapid on-site methodology as described in item 5.1.3.1 and developed by the CSIR has potential for a number of other diseases. This should be pursued if the methodology proves effective for Brucellosis diagnosis.

        Comments: A project towards that goal will be pursued as from 2019.

         

      2. Parasite control supplement:

        Motivation: Addressing resistance of different internal parasites to standard anthelmintic treatment is one of the priorities of the R & D programme. A method to be considered is inclusion of bio-control agents in the concentrate supplement or TMR to cows. One possibility is tannin substances which are toxic to GI tract parasites and which have further advantages (depending on circumstances) of increasing amino acid flow to the small intestine, thereby increasing efficiency of production.

        Comments: A project towards that goal is envisaged already in 2018.

         

      3. Mastitis: Despite the comprehensive attention to the disease, to be effective in reducing its impact, it must be addressed from different angles. Decisions on implementation will depend on the outcomes of projects described in item 5.1.1

        1. Sanitizers:

          Motivation: The efficacy of sanitizers and cleaning solutions should always be tested and new ones identified. Organisms may adapt and biofilms may be difficult to remove. This links to the motivation in item 5.2.1.

          Comments: Attention to sanitizers and cleaning solutions will depend on the outcomes of the project running (item 4.1.2.1), but otherwise is envisaged for 2019.

           

        2. Vaccines:

          Motivation: Vaccination has been investigated with variable success depending on the organism and strain causing mastitis at particular sites. The projects running (items 4.1.2.1 and 4.1.2.2) will identify these species and strains, providing the possibility to develop specific vaccines.

          Comments: Attention to vaccination is envisaged for 2019.

           

        3. AMR management:                                                                                     Motivation: As an alternate to indiscriminate antimicrobial use, specific management plans were introduced in farms involved in regular testing of milk samples. These included parlour hygiene, milker and supervisor education, routine microbiology and cytology examinations and prudent treatment based on susceptibility testing. The study will evaluate the possible impact of these interventions using routine microbiology and cytology of all lactating cows in herds. It will also pay attention to the importance of teat liners in preserving teat integrity and udder health. Comments: Since the data is sourced from an extensive data base the investigations have been initiated as part of the project described in item 5.1.1.1. Envisaged date of completion is 2019.

           

           7.1.4.   Bio-security:

            Motivation: On-farm bio-security measures need to be introduced,

            monitored and benchmarked. A specific focus will be on Bovine

            Brucellosis which will align with the programme by the DAFF/AHF. A

            Code of Bio-security Best Practice should be developed and subscribed

            to by all dairy farmers to limit the introduction and spread of disease as

            well as human and livestock movement to and from farms. It should also

            be recognised that a lack of bio-security measures on farm may be

            associated with zoonotic diseases and the development of food-borne

            illnesses from contamination in the milk lines (see item 6.2.1.)

            Comments: This is urgent and the intended project is moved forward. A

            survey by the MPO is anticipated in 2017, whereas a Code will be

            compiled from several existing bits and pieces by the Programme

            Manager R & D.

            Budget: The costs will be carried by the MPO in 2017 and claimed in

            2018 if required.

           

    2. Feed sources and animal nutrition:

      1. Chicory:                            

        Motivation: New pasture species and varieties should always be a long term priority to support sustainable dairy production from pastures as conditions, cost and efficiency change with time. It is a bonus if species and varieties already integrated or adapted to present pasture mixes but not used to an appreciable extent can be evaluated or improved. Chicory does grow well in present mixes, but does not receive much attention even though it is readily consumed, has high nutritional value and contains tannins which can be of benefit to contain internal parasites (see item 7.1.2).

        Comments: SESCORD (now the Dairy Research Forum) identified evaluation and possibly propagation of chicory as a priority. Since the evaluation will have to be done at departmental stations such as Cedara or Outeniqua the programme will be registered in the provinces and Milk SA will assist with analytical costs. A protocol is envisaged in 2018.

   7.3. Dairy products and nutraceuticals:

 7.3.1.     Anti-candida probiotics:

                Motivation: HIV/AIDS and cancer treatment has major implications,

                amongst others Candida albicans infections. Treatment with antibiotics

                has limitations. If products containing probiotics can be developed

                instead, which can be used regularly, candida infections can be

                prevented. Probiotic strains that are effective have already been

                selected and successfully incorporated in a maize - based drink at the

                TUT. Indications are that a milk or milk-product substrate could be as or

                more effective which makes such a possibility an attractive proposition.

                Irrespective of the viability and impact on broadening of the market, it is

                important that the Dairy Industry is seen to make a contribution to the

                well-being of patients and communities at large.

              Comments: A project will be considered for 2019.

7.3.2.    Probiotics against food-borne pathogens such as Listeria and E.coli:

              Motivation: Food-borne pathogens such as Listeria monocytogenes and

              E. coli 0157H despite HACCP and other controlling measures, are still

              associated with food poisoning; obviously, the problem is worse in

              informal or less controllable value chains. This implies that it is unlikely

               that controlling measures will ever be 100% effective which points to the

              alternative of protecting the population directly. Probiotic strains

              specifically selected against Listeria or E. coli offer such an opportunity

              and should be targeted. A vast array of probiotic strains have proved

              effective in yogurts which suggest yogurt, having additional nutritional 

              and health attributes, as the logical product to be investigated as

              substrate. The addition of long life yogurt to the market offers the further

              advantage of introducing the selected probiotic strains to areas where

              storage cannot be done under optimal conditions.

             Comments: A project will be considered for 2019.

7.3.3.   Milk and dairy product composition:

             Motivation: The nutritional composition of milk and dairy products

             should be re-analysed. The composition of dairy products was analysed in

             1998 and 2006 for selected dairy products. The new regulation

             (Regulation 260), relating to the classification, packing and marking of

             dairy products and imitation dairy products intended for sale in South

             Africa, was introduced in 2016. Regulation 260 allows for changes in the

             fat and protein content of dairy products. One of the important changes

             introduced by R 260, was in the low-fat and medium fat content dairy

             products especially milk, yoghurt and soft cheese. The changes in fat

             -content, impact on the overall nutritional content of the specific product.

                                 The data-base that captures the nutrient content of all foods i.e. Food

                                 Finder, as managed by the Medical Research Council, has been

                                 programmed to use the nutritional information of dairy products as

                                 described in Regulation 2581 (previous regulation) and uses South African

                                 values provided in 1998 and 2006.The Food Finder data base is used to

                                 calculate the nutritional information of different foods for various

                                 purposes e.g. nutritional tables for packaging, dietary recommendations

                                 by dieticians etc. The nutritional composition of milk and selected dairy

                                 products should be re-analysed in order to provide correct values for the

                                 purpose of updating the Food-Finder data base.

                             Comments: A project will be considered for 2019.

    1. Food safety and quality:

             7.4.1    Milk flocculation:

                          Motivation: The current milk flocculation projects are discussed under

                          item 5.2.1. These studies will be supported by statistical analysis of an

                          extended data base of several years of a dairy factory that has experience

                          with the problem of milk flocculation. The statistical analysis will analyse

                          main and interaction effects which should assist in establishing cause and

                          effect, thereby providing a better understanding of the phenomenon.  

                   Comments: The statistical analysis will commence in 2017.

                   Budget: The cost of analysis will depend on the analyst and statistician.

                   The analyst could be internal to the MPO. Costs if required will be

                    reclaimed in 2018.

                   

       

  1. NETWORK IDENTIFIED PROJECTS:

    These projects have been identified through SESCORD (now Dairy Research Forum) and are done elsewhere with no direct financial obligation to Milk SA, but important within the objectives and goals to serve the dairy industry with problem solving R & D.

     

    1. Animal health, bio-security and welfare:

      Animal welfare: Fort Hare – Animal welfare studies are done at Amadlelo facilities.

      Motivation: Animal welfare is both an economic and humane issue. From the humane perspective the Dairy Industry should be seen to do work in this area, even though there are many programmes elsewhere in the world. Lameness may be associated with the studies.

       

    2. Markets and techno-economics:

      Livestock Development: Fort Hare/Döhne – Benchmark project for milk production for emerging farmers in the Eastern Cape.

      Motivation: Milk SA has a dedicated transformation programme funded with statutory levy funds. Information from this project should be valuable for establishing smallholder farmers in the Eastern Cape and also as part of the knowledge base of the Milk SA transformation programme.

               8.3. Environment:

                      8.3.1.   Pasture establishment in the south-eastern seaboard: Outeniqua

                                   Research Institute/Stellenbosch University has a R & D and monitoring

                                   Programme.

                                   Motivation: Monoculture pasture species have implications for bio         

                                   -diversity, ecosystems, eutrophication and water sources. Both under

                                   and heavy fertilization and cattle manure may cause pollution. It is

                                   important that this programme continue and be promoted through the

                                   network.

                                   

                     8.3.2.    Carbon footprint: Outeniqua Research Institute has capacity to measure

                                   GHG and to introduce methodology to limit methane emissions. The

                                   work is supported.

                                   Motivation: Although figures and knowledge on GHG are mostly

                                   available, the DEA is required to report regularly to the IPCC on

                                   mitigation, which require updated figures. The envisaged government

                                   pressure which may lead to taxation could require actual measurements

                                   to demonstrate decreasing trends. This may also require an inventory

                                   and documentation. A further necessity is to initiate work on carbon

                                   sequestration and storage as the potential to limit the carbon footprint

                                   by sequestration and storage is far greater than by limiting carbon

                                   emissions.  

 

                 8.4. Feed sources and animal nutrition:

                     8.4.1.    Pasture cultivar testing/selection: The ARC facility at Cedara has been

                                   Revived and programmes resumed. Cedara (KZN Dept Agriculture) has

                                   Commenced cultivar evaluation trials in collaboration with Outeniqua to

                                   evaluate the same cultivars in a different environment. Outeniqua is

                                   expected to continue with their programme in this regard.

                                   Motivation: Maintenance of and outputs from these facilities are crucial

                                   for the sustainability of pasture-based systems.

 

      1. Forage and roughage sources: Cedara is evaluating Fescue and Outeniqua clovers and silage. Fort Hare is doing surveys for use in smallholder farmer systems.                                                                                                              Motivation: Sustainable establishment, evaluation and improvement of forage sources and storage as quality silage and hay sources should always be considered. Although the ryegrass/kikuyu pasture system is well-established and employed by farmers in the south-eastern seaboard, investigations into alternatives remain important.

         

      2. Pasture establishment on the Highveld: An association with Grass SA, a non-profit company, should be considered to stimulate R & D for this purpose.         

                                  Motivation: Grass SA has infrastructure and facilitates pasture species

                                  testing of importance to dairy farming inland. Costs associated with TMR

                                  systems necessitate increasing introduction of grazing, hay, silage and

                                  haylage when maize silage stock is finished.

             

      3. Concentrate supplementation: Outeniqua and some tertiary institutions are evaluating alternative supplements.                                                                                                      Motivation: Supplements are expensive and the inclusion of less-starch concentrate feed sources that could improve cost effectiveness must be encouraged, also to combat the continuous burden of sub-clinical acidosis (both in TMR and pasture-based systems). The programmes should include ingredients which will reduce methane emission from the rumen (see item 8.3.2) such as the addition of nitrate.